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As Atwoodand Bowen (2011) summarize, this theory is a clear exten-sion of basic antagonistic pleiotropy concepts of aging:“hormones that regulate reproduction act in an antago-nistic pleiotropic manner to control aging via cell cyclesignaling—promoting growth and development early inlife in order to achieve reproduction, but later in life, in afutile attempt to maintain reproduction, become dysregu-lated and drive senescence. (2000) A perspective on infl ammation inAlzheimer’s disease. Before giving a patient with a sus-pected stroke anything to eat or drink were to buy prednisone including medica-tions, the patient should pass a swallow, or dysphagiascreen.
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Increasing concentrations of theantagonist progressively flatten the agonist DRC(Fig.
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The processes are usually conspicuous, inpart because the cells shrink during preparation and a resultantexpanded intercellular space develops between the spines.
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